After the third season of Dan Vs. concluded on March 9, 2013, rumors and speculation of a fourth season were spread. However, on October 17, 2013, the voice of Dan, Curtis Armstrong confirmed on his Facebook page that the series had been cancelled.
"Christian Paredes, James Jones and Larry Reaper, among others, have been kind enough to ask about Dan Vs., the animated series I've been doing for the last few seasons on The Hub. It was created by Chris Pearson and Dan Mandel and also starred Dave Foley and Paget Brewster, giving truly funny performances as Dan's best friend and wife respectively. Dan Vs. actually won an Emmy this year for direction for Dan Angel and was among my favorite past times. It has been canceled, for the baffling and inexplicable reasons that shows like Dan Vs. get canceled. I can't really explain it because it has never been explained to me. Occasionally I would ask about the status of the show and be told that it wasn't canceled, but when I would ask about specifics, there would be long, awkward pauses and then changes to other subjects, like the weather or the possibility of a government shut down (this was the previous government shutdown, which gives you an idea how long this has been going on.) Finally, I had to just give up and move on with my life. This is actually not uncommon in my business. Things just sort of fade away, with an noticeable absence of closure. You can't help dwelling on it for a time, but eventually the whole thing just becomes a sort of fragrant memory. Some fragrances, of course, are sweeter than others: I'm happy to say that in the case of Dan Vs., they are, pretty much across the board, sweet. I loved everyone I worked with, the company was great, the network was supportive and, of course, the fans were rabid and vocal in their enthusiasm. The checks cleared, it's out on DVD and it was fun and you can't really ask for more than that."- Curtis Armstrong's Facebook post.
The Hub Network later rebranded into Discovery Family on October 13, 2014 and the then new network showed no interest in renewing Dan for another season.
Despite rumors circulating that Dan Vs. will be airing on Cartoon Network, there have been no sources stating this from either Cartoon Network or the show creators.
Please take all rumors with a grain of salt and DO NOT SPREAD RUMORS.